Anti-Peptide YY/PYY Antibody

About this product

Boster Bio Anti-Peptide YY/PYY Antibody Picoband® catalog # A04223-1. Tested in IHC applications. This antibody reacts with Human.

Specifications

Catalog number

A04223-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

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Synonyms

Peptide YY; PYY; PYY-I; Peptide tyrosine tyrosine; Peptide YY (3-36) ; PYY-II

Gene Name

PYY

Gene ID

5697

UniProt

P10082

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Peptide YY/PYY, which shares 91.7% amino acid (aa) sequence identity with both mouse and rat Peptide YY/PYY.

Clonality

Polyclonal

Tissue Specificity

Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer. Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer. .

Applications

IHC

Field of Research

Cell Biology, Cell Cycle, Cell Differentiation, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.

References & Citations

1. Liu C, Aloia T, Adrian T, Newton T, Bilchik A, Zinner M, Ashley S, McFadden D (1996) . Peptide YY: a potential proabsorptive hormone for the treatment of malabsorptive disorders. Am Surg 62 (3) : 232–6. 2. Taylor IL (March 1985) . Distribution and release of peptide YY in dog measured by specific radioimmunoassay. Gastroenterology 88 (3) : 731–7.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

87794 MW

Observed Molecular Weight

39 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Peptide YY

Subcellular Location

Secreted.

Protein Name

Transforming acidic coiled-coil-containing protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.