Anti-RBMS3 Antibody Picoband®

About this product

Boster Bio Anti-RBMS3 Antibody Picoband® catalog # A12416-3. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A12416-3

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

RNA-binding motif, single-stranded-interacting protein 3 is a protein that in humans is encoded by the RBMS3 gene. It is mapped to 3p24.1. This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2 (I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

RNA-binding motif, single-stranded-interacting protein 3; RBMS3

Gene Name

RBMS3

Gene ID

27303

UniProt

Q6XE24

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RBMS3 recombinant protein (Position: T350-P437) .

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Applications

ELISA, IF, IHC, ICC, WB

Field of Research

DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling, RNA Processing

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Binds poly (A) and poly (U) oligoribonucleotides.

References & Citations

1. Penkov, D., Ni, R., Else, C., Pinol-Roma, S., Ramirez, F., Tanaka, S. Cloning of a human gene closely related to the genes coding for the c-myc single-strand binding proteins. Gene 243: 27-36, 2000. 2. Kanaoka, Y., Nojima, H. SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins. Nucleic Acids Res. 22: 2687-2693, 1994. 3. Negishi, Y., Nishita, Y., Saegusa, Y., Kakizaki, I., Galli, I., Kihara, F., Tamai, K., Miyajima, N., Iguchi-Ariga, S. M. M., Ariga, H. Identification and cDNA cloning of single-stranded DNA binding proteins that interact with the region upstream of the human c-myc gene. Oncogene 9: 1133-1143, 1994.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

55 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

RNA binding motif single stranded interacting protein 3

Subcellular Location

Cytoplasm.

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.