Anti-Mint3/APBA3 Antibody Picoband®

About this product

Boster Bio Anti-Mint3/APBA3 Antibody Picoband® catalog # A07396-2. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A07396-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Amyloid beta A4 precursor protein-binding family A member 3 is a protein that in humans is encoded by the APBA3 gene. It is mapped to 19p13.3. The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease.

Synonyms

Amyloid-beta A4 precursor protein-binding family A member 3; Adapter protein X11gamma; Neuron-specific X11L2 protein; Neuronal Munc18-1-interacting protein 3; Mint-3; APBA3; MINT3; X11L2

Gene Name

APBA3

Gene ID

9546

UniProt

O96018

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Mint3/APBA3 recombinant protein (Position: Q62-E544) .

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues examined with lower levels in brain and testis.

Applications

ELISA, WB

Field of Research

Interleukins

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.

References & Citations

1. Entrez Gene: APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) . 2. Biederer T, Cao X, Südhof TC, Liu X (Sep 2002) . Regulation of APP-dependent transcription complexes by Mint/X11s: differential functions of Mint isoforms. J. Neurosci. 22 (17) : 7340–51. 3. Tanahashi H, Tabira T (Apr 1999) . X11L2, a new member of the X11 protein family, interacts with Alzheimer's beta-amyloid precursor protein. Biochem Biophys Res Commun. 255 (3) : 663–7.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

108320 MW

Observed Molecular Weight

69 kDa

Specificity

No cross reactivity with other proteins.

Gene Name Synonym

Amyloid beta precursor protein binding family A member 3

Subcellular Location

Perinuclear region.

Protein Name

Gamma-aminobutyric acid type B receptor subunit 1

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.