Anti-Cbx8 Antibody Picoband®

About this product

Boster Bio Anti-Cbx8 Antibody Picoband® catalog # A05234-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05234-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

CBX8 functions as a transcriptional repressor and has a role in DNA damage response. This gene is mapped to chromosome 17q25.3 based on an alignment of the CBX8 sequence with the genomic sequence (GRCh38) .

Synonyms

Zinc finger protein Helios; Ikaros family zinc finger protein 2; IKZF2; HELIOS, ZNFN1A2

Gene Name

CBX8

Gene ID

57332

UniProt

Q9HC52

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Cbx8 recombinant protein (Position: M1-R389) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. High expression in liver, spleen, pancreas and kidney.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Associates with Ikaros at centromeric heterochromatin.

References & Citations

1. Bardos, J. I., Saurin, A. J., Tissot, C., Duprez, E., Freemont, P. S. HPC3 is a new human Polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. J. Biol. Chem. 275: 28785-28792, 2000. 2. Oza, J., Ganguly, B., Kulkarni, A., Ginjala, V., Yao, M., Ganesan, S. A novel role of chromodomain protein CBX8 in DNA damage response. J. Biol. Chem. 291: 22881-22893, 2016. Note: Erratum: J. Biol. Chem. 292: 761 only, 2017.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

39411 MW

Observed Molecular Weight

43-50 kDa

Applications Notes

6

Gene Name Synonym

IKAROS family zinc finger 2

Subcellular Location

Nucleus.

Protein Name

Zinc finger protein Helios

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.