Anti-BCMA/Tnfrsf17 Antibody Picoband®

About this product

Boster Bio Anti-BCMA/Tnfrsf17 Antibody Picoband® catalog # A01014-4. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01014-4

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Synonyms

TNF receptor superfamily member 17

Gene Name

Tnfrsf17

Gene ID

21935

UniProt

O88472

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of mouse BCMA/Tnfrsf17, which shares 78.9% and 95% amino acid (aa) sequence identity with human and rat BCMA/Tnfrsf17, respectively.

Clonality

Polyclonal

Applications

Flow Cytometry, IHC, WB

Field of Research

Antiviral Signaling, Cancer, Growth Factors, Growth Factors/Hormones, Immune System Diseases, Immunology, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

References & Citations

1. Entrez Gene: TNFRSF17 tumor necrosis factor receptor superfamily, member 17. 2. Laabi Y, Gras MP, Brouet JC, Berger R, Larsen CJ, Tsapis A (Apr 1994) . The BCMA gene, preferentially expressed during B lymphoid maturation, is biionally transcribed. Nucleic Acids Research. 22 (7) : 1147–54.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

30 kDa

Applications Notes

6

Gene Name Synonym

TNF receptor superfamily member 17

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.