Anti-Klrd1/CD94 Antibody Picoband®

About this product

Boster Bio Anti-Klrd1/CD94 Antibody Picoband® catalog # A03257-3. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03257-3

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD94 (Cluster of Differentiation 94), also known as killer cell lectin-like receptor subfamily D, member 1 (KLRD1) is a human gene. Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms

Thrombospondin-2; THBS2; TSP2

Gene Name

Klrd1

Gene ID

16643

UniProt

O54707

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse Klrd1/CD94 recombinant protein (Position: N33-I179) .

Clonality

Polyclonal

Tissue Specificity

High expression in invertebral disk tissue.

Applications

WB, ELISA

Field of Research

Calcium Signaling, Calmodulin Pathway, Cardiovascular, Hypertrophy, Neuroscience, Neurotransmission, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500μg/ml.

Function

Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties.

References & Citations

1. Braud, V. M., Allan, D. S. J., O'Callaghan, C. A., Soderstrom, K., D'Andrea, A., Ogg, G. S., Lazetic, S., Young, N. T., Bell, J. I., Phillips, J. H., Lanier, L. L., McMichael, A. J. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature 391: 795-799, 1998. 2. Chang, C., Rodriguez, A., Carretero, M., Lopez-Botet, M., Phillips, J. H., Lanier, L. L. Molecular characterization of human CD94: a type II membrane glycoprotein related to the C-type lectin superfamily. Europ. J. Immun. 25: 2433-2437, 1995. 3. Lazetic, S., Chang, C., Houchins, J. P., Lanier, L. L., Phillips, J. H. Human natural killer cell receptors involved in MHC class I recognition are disulfide-linked heterodimers of CD94 and NKG2 subunits. J. Immun. 157: 4741-4745, 1996.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

30 kDa

Gene Name Synonym

Thrombospondin 2

Subcellular Location

Synapse. Postsynaptic density. Dendritic spine. Dendrite.

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.005mg NaN3.