Anti-SV2A Antibody Picoband®

About this product

Boster Bio Anti-SV2A Antibody Picoband® catalog # A03752-3. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03752-3

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Synaptic vesicle glycoprotein 2A is a ubiquitous synaptic vesicle protein that in humans is encoded by the SV2A gene. The protein encoded by this gene is one of three related synaptic vesicle proteins. The encoded protein may interact with synaptotagmin to enhance low frequency neurotransmission in quiescent neurons.

Synonyms

Sodium/glucose cotransporter 2; Na (+) /glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2; SLC5A2; SGLT2

Gene Name

SV2A

Gene ID

9900

UniProt

Q7L0J3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human SV2A, identical to the related mouse and rat sequences.

Clonality

Polyclonal

Applications

Flow Cytometry, IHC, WB

Field of Research

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.

References & Citations

1. Bajjalieh, S. M., Peterson, K., Linial, M., Scheller, R. H. Brain contains two forms of synaptic vesicle protein 2. Proc. Nat. Acad. Sci. 90: 2150-2154, 1993. 2. Crowder, K. M., Gunther, J. M., Jones, T. A., Hale, B. D., Zhang, H. Z., Peterson, M. R., Scheller, R. H., Chavkin, C., Bajjalieh, S. M. Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A) . Proc. Nat. Acad. Sci. 96: 15268-15273, 1999. 3. Dong, M., Yeh, F., Tepp, W. H., Dean, C., Johnson, E. A., Janz, R., Chapman, E. R. SV2 is the protein receptor for botulinum neurotoxin A. Science 312: 592-596, 2006.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

110 kDa

Applications Notes

6

Gene Name Synonym

Solute carrier family 5 member 2

Subcellular Location

Membrane. Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.