Anti-SCC112/PDS5A Antibody Picoband®

About this product

Boster Bio Anti-SCC112/PDS5A Antibody Picoband® catalog # A06272-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A06272-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Sister chromatid cohesion protein PDS5 homolog A is a protein that in humans is encoded by the PDS5A gene. The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

ELAV-like protein 2; ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1; ELAVL2; HUB

Gene Name

PDS5A

Gene ID

23244

UniProt

Q29RF7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PDS5A recombinant protein (Position: M1-R1337) .

Clonality

Polyclonal

Tissue Specificity

Brain; neural-specific.

Applications

WB, ICC, IF, Flow Cytometry, ELISA

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, RNA Processing

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.

References & Citations

1. Ishikawa, K., Nagase, T., Suyama, M., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 169-176, 1998. 2. Kumar, D., Sakabe, I., Patel, S., Zhang, Y., Ahmad, I., Gehan, E. A., Whiteside, T. L., Kasid, U. SCC-112, a novel cell cycle-regulated molecule, exhibits reduced expression in human renal carcinomas. Gene 328: 187-196, 2004. 3. Terret, M.-E., Sherwood, R., Rahman, S., Qin, J., Jallepalli, P. V. Cohesin acetylation speeds the replication fork. Nature 462: 231-234, 2009.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

49655 MW

Observed Molecular Weight

151 kDa

Applications Notes

6

Gene Name Synonym

ELAV like RNA binding protein 2

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm.

Protein Name

AP-2 complex subunit mu

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.