Anti-SUMO2/3 Antibody Picoband®

About this product

Boster Bio Anti-SUMO2/3 Antibody Picoband® catalog # A01282-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01282-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Small ubiquitin-related modifier 2,3 is a protein that in humans is encoded by the SUMO2,3 gene. This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms

CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; CD81; Cd81; Tapa1

Gene Name

SUMO2/3

Gene ID

6613/6612

UniProt

P61956/P55854

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SUMO2/3 recombinant protein (Position: Q24-T72) .

Clonality

Polyclonal

Tissue Specificity

Expressed in oocytes. Highly expressed in granulosa cells.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Adaptive Immunity, B Cells, Host-Virus Interaction, Human Protein, Immunology, Interspecies Interaction, Microbiology, Protein

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

May play an important role in the regulation of lymphoma cell growth. May be involved in the acrosome reaction.

References & Citations

1. Adams, M. D., Soares, M. B., Kerlavage, A. R., Fields, C., Venter, J. C. Rapid cDNA sequencing (expressed sequence tags) from a ionally cloned human infant brain cDNA library. Nature Genet. 4: 373-380, 1993. 2. Dai, K.-S., Liew, C.-C. A novel human striated muscle RING zinc finger protein, SMRZ, interacts with SMT3b via its RING domain. J. Biol. Chem. 276: 23992-23999, 2001. 3. Lapenta, V., Chiurazzi, P., van der Spek, P., Pizzuti, A., Hanaoka, F., Brahe, C. SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family. Genomics 40: 362-366, 1997.

Storage Conditions

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Observed Molecular Weight

20 kDa

Applications Notes

6

Gene Name Synonym

CD81 antigen

Subcellular Location

Basolateral cell membrane.

Isotype

Rabbit IgG

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.