Anti-Cd19 Antibody

About this product

Boster Bio Anti-Cd19 Antibody Picoband® catalog # A00154-4. Tested in ELISA, IHC applications. This antibody reacts with Rat.

Specifications

Catalog number

A00154-4

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

B-lymphocyte antigen CD19, also known as CD19 (Cluster of Differentiation 19), is a protein that in humans is encoded by the CD19 gene. It is found on the surface of B-cells, a type of white blood cell. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. The CD19 gene encodes a cell surface molecule that assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Synonyms

B-lymphocyte antigen CD19; Differentiation antigen CD19; CD19; Cd19

Gene Name

Cd19

Gene ID

365367

UniProt

F1LNH2

Host

Rabbit

Reactivity

Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived rat Cd19 recombinant protein (Position: D89-L420) .

Clonality

Polyclonal

Applications

IHC, ELISA

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

References & Citations

1. Entrez Gene: CD19 CD19 molecule. 2. Pesando JM, Bouchard LS, McMaster BE (Dec 1989) . CD19 is functionally and physically associated with surface immunoglobulin. The Journal of Experimental Medicine 170 (6) : 2159–64. 3. Tedder TF, Isaacs CM (Jul 1989) . Isolation of cDNAs encoding the CD19 antigen of human and mouse B lymphocytes. A new member of the immunoglobulin superfamily. Journal of Immunology 143 (2) : 712–7.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

85 kDa

Gene Name Synonym

CD19 antigen

Subcellular Location

Membrane; Single-pass type I membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.