Anti-MSL2 Antibody Picoband®

About this product

Boster Bio Anti-MSL2 Antibody Picoband® catalog # A02712-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02712-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

MSL2 (MSL Complex Subunit 2) is a protein coding gene located on human chromosome 3q22.3. MSL2 is also known as MSL-2, MSL2L1 and RNF184. The human MSL2 gene encodes a 62541 Da protein containing 577 amino acids. The MSL2 protein is ubiquitously expressed in bone marrow, lymph node and other tissues. Among its related pathways are Chromatin organization and Chromatin Regulation / Acetylation. MSL2 is related to ligase activity. MSL2 is associated with some diseases, such as Atrial Septal Defect 3.

Synonyms

Short transient receptor potential channel 5; TrpC5; Transient receptor protein 5; TRP-5; hTRP-5; hTRP5; TRPC5; TRP5

Gene Name

MSL2

Gene ID

55167

UniProt

Q9HCI7

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human MSL2 recombinant protein (Position: M1-C577) .

Clonality

Polyclonal

Tissue Specificity

Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole.

Applications

ELISA, Flow Cytometry, IF, ICC, WB

Field of Research

Calcium Channels, Calcium Signaling, Metabolism, Neuroscience, Neurotransmission, Plasma Membrane, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/31/2012. 2. Nagase, T., Kikuno, R., Nakayama, M., Hirosawa, M., Ohara, O. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 7: 273-281, 2000. 3. Smith, E. R., Cayrou, C., Huang, R., Lane, W. S., Cote, J., Lucchesi, J. C. A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. Molec. Cell. Biol. 25: 9175-9188, 2005. Note: Erratum: Molec. Cell. Biol. 26: 387 only, 2006.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

91791 MW

Observed Molecular Weight

63 kDa

Applications Notes

6

Gene Name Synonym

Transient receptor potential cation channel subfamily C member 5

Subcellular Location

Cell membrane. Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.