Anti-ME1 Antibody Picoband®

About this product

Boster Bio Anti-ME1 Antibody Picoband® catalog # A03449-3. Tested in ELISA, Flow Cytometry, IF, ICC/IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03449-3

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

NADP-dependent malic enzyme is a protein that in humans is encoded by the ME1 gene. This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet.

Synonyms

High affinity copper uptake protein 1; Copper transporter 1; hCTR1; Solute carrier family 31 member 1; SLC31A1; COPT1; CTR1

Gene Name

ME1

Gene ID

4199

UniProt

P48163

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human ME1 recombinant protein (Position: M1-Q572) .

Clonality

Polyclonal

Tissue Specificity

Found in the synovial fluid of patients with rheumatoid arthritis. .

Applications

WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA

Field of Research

Neuroscience, Neurotransmission, Receptors / Channels

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

High-affinity, saturable copper transporter involved in dietary copper uptake.

References & Citations

1. Chen, T.-R., McMorris, F. A., Creagan, R., Ricciuti, F. C., Tischfield, J., Ruddle, F. H. Assignment of the genes for malate oxidoreductase decarboxylating to chromosome 6 and peptidase B and lactate dehydrogenase B to chromosome 12 in man. Am. J. Hum. Genet. 25: 200-207, 1973. 2. Cohen, P. T. W., Omenn, G. S. Genetic variation of the cytoplasmic and mitochondrial malic enzymes in the monkey: Macaca nemestrina. Biochem. Genet. 7: 289-301, 1972. 3. Gimelbrant, A., Hutchinson, J. N., Thompson, B. R., Chess, A. Widespread monoallelic expression on human autosomes. Science 318: 1136-1140, 2007.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

64 kDa

Observed Molecular Weight

64 kDa

Applications Notes

6

Gene Name Synonym

Solute carrier family 31 member 1

Subcellular Location

Cell membrane; Localizes to the apical membrane in intestinal epithelial cells.

Protein Name

Tumor necrosis factor-inducible gene 6 protein

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.