Anti-Annexin-4/ANXA4 Antibody Picoband®

About this product

Boster Bio Anti-Annexin-4/ANXA4 Antibody Picoband® catalog # A04840-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04840-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

ANXA4 (Annexin A4), also known as ANX4, is a protein that in humans is encoded by the ANXA4 gene. It belongs to the annexin family of calcium-dependent phospholipid binding proteins. By PCR analysis of somatic cell hybrids and in situ hybridization with a cDNA probe, the human ANXA4 gene is mapped to chromosome 2p13. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. And ANXA4 is almost exclusively expressed in epithelial cells.

Synonyms

Annexin A4;35-beta calcimedin; Annexin IV; Annexin-4; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; Lipocortin IV; P32.5; PP4-X; Placental anticoagulant protein II; PAP-II; Protein II; ANXA4; ANX4

Gene Name

ANXA4

Gene ID

307

UniProt

P09525

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Annexin-4/ANXA4 recombinant protein (Position: M1-D319) .

Clonality

Polyclonal

Tissue Specificity

Expressed at high levels in lung, placenta and thymus and at lower levels in ovary, intestine and brain.

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Calcium Binding Proteins, Calcium Signaling, Cardiovascular, Cell Adhesion, Cytoskeleton/ECM, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. .

References & Citations

1. Barrow, L. L., Simin, K., Jones, J. M., Lee, D. C., Meisler, M. H. Conserved linkage of early growth response 4, annexin 4, and transforming growth factor alpha on mouse chromosome 6. Genomics 19: 388-390, 1994. 2. Fukuoka, S.-I., Kern, H., Kazuki-Sugino, R., Ikeda, Y. Cloning and characterization of ZAP36, an annexin-like, zymogen granule membrane associated protein, in exocrine pancreas. Biochim. Biophys. Acta 1575: 148-152, 2002. 3. Tait, J. F., Smith, C., Frankenberry, D. A., Miao, C. H., Adler, D. A., Disteche, C. M. Chromosomal mapping of the human annexin IV (ANX4) gene. Genomics 12: 313-318, 1992.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

35883 MW

Observed Molecular Weight

36 kDa

Applications Notes

6

Gene Name Synonym

Annexin A4

Subcellular Location

Nucleus.

Protein Name

Annexin A4

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.