Anti-delta 1 Catenin/CAS/CTNND1 Antibody Picoband® (monoclonal, 8G7E4)

About this product

Boster Bio Anti-delta 1 Catenin/CAS/CTNND1 Antibody Picoband® (monoclonal, 8G7E4) catalog # M02333-2. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

M02333-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

P120, and called catenin delta-1 is a protein that in humans is encoded by the CTNND1 gene. This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene.

Synonyms

Adenosine kinase; AK; Adenosine 5'-phosphotransferase; ADK

Gene Name

CTNND1

Gene ID

1500

UniProt

O60716

Host

Mouse

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human delta 1 Catenin/CAS/CTNND1 recombinant protein (Position: H64-K930) .

Clonality

Monoclonal

Clone

Clone: 8G7E4

Tissue Specificity

Widely expressed. Highest level in placenta, liver, muscle and kidney.

Applications

WB, IHC, ICC, IF

Field of Research

DNA/RNA, Epigenetics and Nuclear Signaling, Ribosome, RNA Processing, Translation

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

References & Citations

1. Bonne, S., van Hengel, J., van Roy, F. Chromosomal mapping of human armadillo genes belonging to the p120 (ctn) /plakophilin subfamily. Genomics 51: 452-454, 1998. 2. Dillon, D. A., D'Aquila, T., Reynolds, A. B., Fearon, E. R., Rimm, D. L. The expression of p120ctn protein in breast cancer is independent of alpha- and beta-catenin and E-cadherin. Am. J. Path. 152: 75-82, 1998. 3. Ghoumid, J., Stichelbout, M., Jourdain, A.-S., Frenois, F., Lejeune-Dumoulin, S., Alex-Cordier, M.-P., Lebrun, M., Guerreschi, P., Duquennoy-Martinot, V., Vinchon, M., Ferri, J., Jung, M., Vicaire, S., Vanlerberghe, C., Escande, F., Petit, F., Manouvrier-Hanu, S. Blepharocheilodontic syndrome is a CDH1 pathway-related disorder due to mutations in CDH1 and CTNND1. Genet. Med. 19: 1013-1021, 2017.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

100 kDa

Gene Name Synonym

Adenosine kinase

Subcellular Location

Nucleus. Cytoplasm.

Protein Name

Mitofusin-1

Isotype

Mouse IgG2b

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.