Anti-DHX29 Antibody Picoband®

About this product

Boster Bio Anti-DHX29 Antibody Picoband® catalog # A07866. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A07866

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

DExH-box helicase 29 (DHX29) is a 155 kDa protein that in humans is encoded by the DHX29 gene. This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein functions in translation initiation, and is specifically required for ribosomal scanning across stable mRNA secondary structures during initiation codon selection. This protein may also play a role in sensing virally derived cytosolic nucleic acids. Knockdown of this gene results in reduced protein translation and impaired proliferation of cancer cells.

Synonyms

Fascin-2; Retinal fascin; FSCN2

Gene Name

DHX29

Gene ID

54505

UniProt

Q7Z478

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human DHX29 recombinant protein (Position: R56-K1343) .

Clonality

Polyclonal

Tissue Specificity

Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 4/1/2009. 2. Pisareva, V. P., Pisarev, A. V., Komar, A. A., Hellen, C. U. T., Pestova, T. V. Translation initiation on mammalian mRNAs with structured 5-prime UTRs requires DExH-box protein DHX29. Cell 135: 1237-1250, 2008.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

49229 MW

Observed Molecular Weight

155 kDa

Applications Notes

6

Gene Name Synonym

Fascin actin-bundling protein 2, retinal

Subcellular Location

Nucleus.

Protein Name

Chromaffin granule amine transporter

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.