Anti-DP2/TFDP2 Antibody Picoband®

About this product

Boster Bio Anti-DP2/TFDP2 Antibody Picoband® catalog # A06850-3. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A06850-3

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Transcription factor Dp-2 is a protein that in humans is encoded by the TFDP2 gene. The gene is a member of the transcription factor DP family. The encoded protein forms heterodimers with the E2F transcription factors resulting in transcriptional activation of cell cycle regulated genes. Alternative splicing results in multiple transcript variants.

Synonyms

Intraflagellar transport protein 88 homolog; Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10; IFT88; TG737; TTC10

Gene Name

TFDP2

Gene ID

7029

UniProt

Q14188

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human DP2/TFDP2, identical to the related mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Expressed in the heart, brain, liver, lung, kidney, skeletal muscle and pancreas.

Applications

WB

Field of Research

Cell Adhesion Proteins, ECM Proteins, Neuroscience

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Involved in primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

References & Citations

1. Zhang, Y., Chellappan, S. P. Cloning and characterization of human DP2, a novel dimerization partner of E2F. Oncogene 10: 2085-2093, 1995. 2. Zhang, Y., Venkatraj, V. S., Fischer, S. G., Warburton, D., Chellappan, S. P. Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family. Genomics 39: 95-98, 1997.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

104553 MW

Observed Molecular Weight

49 kDa

Gene Name Synonym

Intraflagellar transport 88

Subcellular Location

Centriole. Cilium basal body. Centrosome. Cilium. Cytoplasm. Flagellum.

Protein Name

AP-2 complex subunit beta

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.