Anti-Epoxide hydrolase/EPHX1 Antibody Picoband®

About this product

Boster Bio Anti-Epoxide hydrolase/EPHX1 Antibody Picoband® catalog # A00899-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A00899-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Epoxide hydrolase 1 is an enzyme encoded by the EPHX1 gene in humans. Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Synonyms

Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; FSHR; LGR1

Gene Name

EPHX1

Gene ID

2052

UniProt

P07099

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Epoxide hydrolase/EPHX1 recombinant protein (Position: A42-Q455) .

Clonality

Polyclonal

Tissue Specificity

Sertoli cells and ovarian granulosa cells.

Applications

ELISA, Flow Cytometry, WB

Field of Research

Endocrine System, G Protein Signaling, More Gpcr, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

References & Citations

1. Brown, S., Chalmers, D. E. Microsomal epoxide hydrolase activity in human x mouse hybrid cells. Biochem. Biophys. Res. Commun. 137: 775-780, 1986. 2. Hamosh, A. Personal Communication. Baltimore, Md. September 20, 2017. 3. Hartsfield, J. K., Jr., Sutcliffe, M. J., Everett, E. T., Hassett, C., Omiecinski, C. J., Saari, J. A. Assignment of microsomal epoxide hydrolase (EPHX1) to human chromosome 1q42.1 by in situ hybridization. Cytogenet. Cell Genet. 83: 44-45, 1998.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

78265 MW

Observed Molecular Weight

53 kDa

Applications Notes

6

Gene Name Synonym

Follicle-stimulating hormone receptor

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Name

Follicle-stimulating hormone receptor (FSH-R)

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.