Anti-THBS3 Antibody Picoband®

About this product

Boster Bio Anti-THBS3 Antibody Picoband® catalog # A11652-2. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A11652-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Thrombospondin-3 (TSP3) is a protein that in humans is encoded by the THBS3 gene. The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants.

Synonyms

Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166; EVA1A; FAM176A; TMEM166; SP24

Gene Name

THBS3

Gene ID

7059

UniProt

P49746

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human THBS3 recombinant protein (Position: Q23-T486) .

Clonality

Polyclonal

Tissue Specificity

Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Cell Biology, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin E3 Enzymes

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.

References & Citations

1. Adolph, K. W., Long, G. L., Winfield, S., Ginns, E. I., Bornstein, P. Structure and organization of the human thrombospondin 3 gene (THBS3) . Genomics 27: 329-336, 1995. 2. Bornstein, P., Devarayalu, S., Edelhoff, S., Disteche, C. M. Isolation and characterization of the mouse thrombospondin 3 (Thbs3) gene. Genomics 15: 607-613, 1993. 3. Bornstein, P., McKinney, C. E., LaMarca, M. E., Winfield, S., Shingu, T., Devarayalu, S., Vos, H. L., Ginns, E. I. Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease. Proc. Nat. Acad. Sci. 92: 4547-4551, 1995.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

120 kDa

Applications Notes

6

Gene Name Synonym

Eva-1 homolog A, regulator of programmed cell death

Subcellular Location

Endoplasmic reticulum membrane, Single-pass membrane protein, Lysosome membrane.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.