Anti-TMEM97 Antibody Picoband®

About this product

Boster Bio Anti-TMEM97 Antibody Picoband® catalog # A08336-1. Tested in ELISA, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08336-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

TMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels .

Synonyms

Histone-lysine N-methyltransferase SETDB2; Chronic lymphocytic leukemia deletion region gene 8 protein; Lysine N-methyltransferase 1F; SET domain bifurcated 2; SETDB2; C13orf4; CLLD8; KMT1F

Gene Name

TMEM97

Gene ID

27346

UniProt

Q5BJF2

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TMEM97 recombinant protein (Position: A5-L141) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in reproductive organs, such as testis, ovary and prostate.

Applications

WB, ELISA

Field of Research

Immune System Diseases, Immunology, Protein Trafficking, Signal Transduction, Signaling Pathway

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3) . H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

References & Citations

1. Bartz, F., Kern, L., Erz, D., Zhu, M., Gilbert, D., Meinhof, T., Wirkner, U., Erfle, H., Muckenthaler, M., Pepperkok, R., Runz, H. Identification of cholesterol-regulating genes by targeted RNAi screening. Cell Metab. 10: 63-75, 2009. 2. Kayed, H., Kleeff, J., Ding, J., Hammer, J., Giese, T., Zentgraf, H., Buchler, M. W., Friess, H. Expression analysis of MAC30 in human pancreatic cancer and tumors of the gastrointestinal tract. Histol. Histopath. 19: 1021-1031, 2004. 3. Malhotra, K., Luehrsen, K. R., Costello, L. L., Raich, T. J., Sim, K., Foltz, L., Davidson, S., Xu, H., Chen, A., Yamanishi, D. T., Lindemann, G. W., Cain, C. A., Madlansacay, M. R., Hashima, S. M., Pham, T. L., Mahoney, W., Schueler, P. A. Identification of differentially expressed mRNAs in human fetal liver across gestation. Nucleic Acids Res. 27: 839-847, 1999.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

23 kDa

Gene Name Synonym

SET domain bifurcated histone lysine methyltransferase 2

Subcellular Location

Nucleus. Chromosome.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.