Anti-TREML2 Antibody Picoband®

About this product

Boster Bio Anti-TREML2 Antibody Picoband® catalog # A08894-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08894-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

TREML2 is a single-pass type I membrane protein, and it contains 1 Ig-like V-type (immunoglobulin-like) domain. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 and TREM2, but it has distinct structural and functional properties.

Synonyms

Pannexin-2; PANX2

Gene Name

TREML2

Gene ID

79865

UniProt

Q5T2D2

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TREML2 recombinant protein (Position: E64-I321) .

Clonality

Polyclonal

Tissue Specificity

Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Organelles, Subcellular Markers, Tags & Cell Markers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Structural component of the gap junctions and the hemichannels.

References & Citations

1. Allcock, R. J. N., Barrow, A. D., Forbes, S., Beck, S., Trowsdale, J. The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. Europ. J. Immun. 33: 567-577, 2003. 2. Benitez, B. A., Jin, S. C., Guerreiro, R., Graham, R., Lord, J., Harold, D., Sims, R., Lambert, J.-C., Gibbs, J. R., Bras, J., Sassi, C., Harari, O., and 34 others. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiol. Aging 35: e19-e26, 2014. Note: Electronic Article.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

70 kDa

Applications Notes

6

Gene Name Synonym

Pannexin 2

Subcellular Location

Cell membrane. Multi-pass membrane protein. Gap junction.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.