Anti-SEL1L Antibody Picoband®

About this product

Boster Bio Anti-SEL1L Antibody Picoband® catalog # A03343-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03343-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Protein sel-1 homolog 1 is a protein that in humans is encoded by the SEL1L gene. The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Synonyms

Glutathione S-transferase Mu 3; GST class-mu 3; GSTM3-3; hGSTM3-3; GSTM3; GST5

Gene Name

SEL1L

Gene ID

6400

UniProt

Q9UBV2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SEL1L recombinant protein (Position: E105-E723) .

Clonality

Polyclonal

Tissue Specificity

Testis and brain.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Cancer, Drug Metabolism, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.

References & Citations

1. Biunno, I., Appierto, V., Cattaneo, M., Leone, B. E., Balzano, G., Socci, C., Saccone, S., Letizia, A., Valle, G. D., Sgaramella, V. Isolation of a pancreas-specific gene located on human chromosome 14q31: expression analysis in human pancreatic ductal carcinomas. Genomics 46: 284-286, 1997. 2. Cattaneo, M., Canton, C., Albertini, A., Biunno, I. Identification of a region within SEL1L protein required for tumour growth inhibition. Gene 326: 149-156, 2004. 3. Donoviel, D. B., Bernstein, A. SEL-1L maps to human chromosome 14, near the insulin-dependent diabetes mellitus locus 11. Genomics 56: 232-233, 1999.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

100 kDa

Applications Notes

6

Gene Name Synonym

Glutathione S-transferase mu 3

Subcellular Location

Cytoplasm.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.