Anti-SFR1 Antibody Picoband®

About this product

Boster Bio Anti-SFR1 Antibody Picoband® catalog # A07683-1. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A07683-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

SFR1 is a component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination.

Synonyms

Trem-like transcript 1 protein; TLT-1; Triggering receptor expressed on myeloid cells-like protein 1; TREML1; TLT1; UNQ1825/PRO3438

Gene Name

SFR1

Gene ID

119392

UniProt

Q86XK3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human SFR1.

Clonality

Polyclonal

Tissue Specificity

Detected in platelets, monocytic leukemia and in T-cell leukemia. .

Applications

WB, Flow Cytometry

Field of Research

Cardiovascular, Immunology, Innate Immunity, Macrophage/Inflammation, Platelets, Protein Phosphorylation, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Cell surface receptor that may play a role in the innate and adaptive immune response. .

References & Citations

1. Akamatsu, Y., Jasin, M. Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination. PLoS Genet. 6: e1001160, 2010. Note: Electronic Article. 2. Feng, Y., Singleton, D., Guo, C., Gardner, A., Pakala, S., Kumar, R., Jensen, E., Zhang, J., Khan, S. DNA homologous recombination factor SFR1 physically and functionally interacts with estrogen receptor alpha. PLoS One 8: e68075, 2013. Note: Electronic Article. 3. Hartz, P. A. Personal Communication. Baltimore, Md. 8/17/2015.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

32679 MW

Observed Molecular Weight

22 kDa

Applications Notes

6

Gene Name Synonym

Trem-like transcript 1 protein

Subcellular Location

Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151) . Transported to the cell surface after stimulation by thrombin (PubMed:15100151) . Soluble fragments can be released into the serum by proteolysis (PubMed:16505478) .

Protein Name

Trem-like transcript 1 protein

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.