Anti-TTC7B Antibody Picoband®

About this product

Boster Bio Anti-TTC7B Antibody Picoband® catalog # A12170-1. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A12170-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane. The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns (4) P) synthesis. In the complex, plays a central role in bridging PI4KA to EFR3B and FAM126A, via interactions

Synonyms

Mitochondrial import inner membrane translocase subunit Tim17-A; Inner membrane preprotein translocase Tim17a; TIMM17A; MIMT17; TIM17; TIM17A; TIMM17

Gene Name

TTC7B

Gene ID

145567

UniProt

Q86TV6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human TTC7B recombinant protein (Position: E275-H730) .

Clonality

Polyclonal

Applications

ELISA, Flow Cytometry, IF, IHC, WB

Field of Research

Cancer, Metabolism, Mitochondrial Metabolism, Organelle Proteins, Pathways and Processes, Protein Trafficking, Signal Transduction, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.

References & Citations

1. Baskin, J. M. , Wu, X. , Christiano, R. , Oh, M. S. , & Camilli, P. D. . (2016) . The leukodystrophy protein fam126a (hyccin) regulates ptdins (4) p synthesis at the plasma membrane. Nature Cell Biology, 18 (1), 132.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

94 kDa

Applications Notes

6

Gene Name Synonym

Translocase of inner mitochondrial membrane 17A

Subcellular Location

Mitochondrion inner membrane, Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.