Anti-FATP4/SLC27A4 Antibody Picoband®

About this product

Boster Bio Anti-FATP4/SLC27A4 Antibody Picoband® catalog # A05299-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05299-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Long-chain fatty acid transport protein 4 is a protein that in humans is encoded by the SLC27A4 gene. This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome.

Synonyms

Loricrin; LOR; LRN

Gene Name

SLC27A4

Gene ID

10999

UniProt

Q6P1M0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human FATP4/SLC27A4 recombinant protein (Position: K15-L643) .

Clonality

Polyclonal

Tissue Specificity

Expressed in testis and to a lesser degree in brain, ovary and placenta. Found in most tissues at low levels.

Applications

ELISA, IHC, WB

Field of Research

Cell Biology, Cytokines, Epigenetics and Nuclear Signaling, Immunology, Innate Immunity, Interferons, Proteasome / Ubiquitin, Proteolysis/Ubiquitin, Ubiquitin & Ubiquitin Like Modifiers, Ubiquitin E3 Enzymes

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Major keratinocyte cell envelope protein.

References & Citations

1. Esperon-Moldes, U. S., Ginarte, M., Santamarina, M., Rodriguez-Lage, B., Rodriguez-Pazos, L., Vega, A. Novel compound heterozygous FATP4 mutations caused ichthyosis prematurity syndrome in Spanish sisters. Acta Paediat. 108: 763-765, 2019. 2. Gertow, K., Bellanda, M., Eriksson, P., Boquist, S., Hamsten, A., Sunnerhagen, M., Fisher, R. M. Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome. J. Clin. Endocr. Metab. 89: 392-399, 2004. 3. Hirsch, D., Stahl, A., Lodish, H. F. A family of fatty acid transporters conserved from mycobacterium to man. Proc. Nat. Acad. Sci. 95: 8625-8629, 1998.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

39411 MW

Observed Molecular Weight

70 kDa

Gene Name Synonym

Loricrin

Subcellular Location

Nucleoplasm. Cytoplasm.

Protein Name

Zinc finger protein Helios

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.