Anti-Spermine synthase/SMS Antibody Picoband®

About this product

Boster Bio Anti-Spermine synthase/SMS Antibody Picoband® catalog # A01831-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A01831-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a protein belonging to the spermidine/spermin synthase family and catalyzes the production of spermine from spermidine. Pseudogenes of this gene are located on chromosomes 1, 5, 6 and X. Mutations in this gene cause an X-linked intellectual disability called Snyder-Robinson Syndrome (SRS) . Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Beta-galactosidase; Glb1; Glb1_mapped; rCG_25043

Gene Name

SMS

Gene ID

6611

UniProt

P52788

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Spermine synthase/SMS recombinant protein (Position: Q102-K365) .

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Field of Research

Neuroscience, Stem Cells, Synapse Marker, T Cells, T Lymphocytic Lineage

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.EC:3.2.1.23

References & Citations

1. Becerra-Solano, L. E., Butler, J., Castaneda-Cisneros, G., McCloskey, D. E., Wang, X., Pegg, A. E., Schwartz, C. E., Sanchez-Corona, J., Garcia-Ortiz, J. E. A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome. Am. J. Med. Genet. 149A: 328-335, 2009. 2. Cason, A. L., Ikeguchi, Y., Skinner, C., Wood, T. C., Holden, K. R., Lubs, H. A., Martinez, F., Simensen, R. J., Stevenson, R. E., Pegg, A. E., Schwartz, C. E. X-linked spermine synthase gene (SMS) defect: the first polyamine deficiency syndrome. Europ. J. Hum. Genet. 11: 937-944, 2003. 3. de Alencastro, G., McCloskey, D. E., Kliemann, S. E., Maranduba, C. M. C., Pegg, A. E., Wang, X., Bertola, D. A., Schwartz, C. E., Passos-Bueno, M. R., Sertie, A. L. New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder-Robinson X-linked recessive mental retardation syndrome. (Letter) J. Med. Genet. 45: 539-543, 2008.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

18080 MW

Observed Molecular Weight

41 kDa

Applications Notes

6

Gene Name Synonym

Galactosidase, beta 1

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Thy-1 membrane glycoprotein

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.