Anti-SNRNP40 Antibody Picoband®

About this product

Boster Bio Anti-SNRNP40 Antibody Picoband® catalog # A12991-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A12991-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs.

Synonyms

Alpha-amylase 1;3.2.1.1;1,4-alpha-D-glucan glucanohydrolase 1; Salivary alpha-amylase; AMY1A; AMY1; AMY1B; AMY1; AMY1C; AMY1

Gene Name

SNRNP40

Gene ID

9410

UniProt

Q96DI7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human SNRNP40 recombinant protein (Position: A43-Q357) .

Clonality

Polyclonal

Tissue Specificity

Highly expressed in the kidney, brain and testis and to a lower extent in heart, liver and small intestine. Expressed in the lens, cornea and retina. Strongly expressed in the distal tips of the retinal neuroepithelium that form the iris and ciliary body.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Complement, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

References & Citations

1. Achsel, T., Ahrens, K., Brahms, H., Teigelkamp, S., Luhrmann, R. The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein. Molec. Cell. Biol. 18: 6756-6766, 1998. 2. Gross, M. B. Personal Communication. Baltimore, Md. 5/16/2011. 3. Neubauer, G., King, A., Rappsilber, J., Calvio, C., Watson, M., Ajuh, P., Sleeman, J., Lamond, A., Mann, M. Mass spectrometry and EST-database searching allows characterisation of the multi-protein spliceosome complex. Nature Genet. 20: 46-50, 1998.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

57768 MW

Observed Molecular Weight

37 kDa

Applications Notes

6

Gene Name Synonym

Alpha-amylase 1

Subcellular Location

Secreted.

Protein Name

Alpha-amylase 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.