Anti-U1A/SNRPA Antibody Picoband®

About this product

Boster Bio Anti-U1A/SNRPA Antibody Picoband® catalog # A08780-2. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08780-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

U1 small nuclear ribonucleoprotein A is a protein that in humans is encoded by the SNRPA gene. The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

Synonyms

Epidermal growth factor-like protein 6; EGF-like protein 6; MAM and EGF domains-containing gene protein; EGFL6; MAEG; PP648; UNQ281/PRO320

Gene Name

SNRPA

Gene ID

6626

UniProt

P09012

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human U1A/SNRPA recombinant protein (Position: E25-E218) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous.

Applications

WB, IHC, ICC, IF, ELISA

Field of Research

Growth Factors/Hormones, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity) .

References & Citations

1. Nelissen, R. L. H., Sillekens, P. T. G., Beijer, R. P., Geurts van Kessel, A. H. M., van Venrooij, W. J. Structure, chromosomal localization and evolutionary conservation of the gene encoding human U1 snRNP-specific A protein. Gene 102: 189-196, 1991. 2. Schonk, D., van Dijk, P., Riegmann, P., Trapman, J., Holm, C., Willcocks, T. C., Sillekens, P., van Venrooij, W., Wimmer, E., Geurts van Kessel, A., Ropers, H.-H., Wieringa, B. Assignment of seven genes to distinct intervals on the midportion of human chromosome 19q surrounding the myotonic dystrophy gene region. Cytogenet. Cell Genet. 54: 15-19, 1990. 3. Sillekens, P. T. G., Habets, W. J., Beijer, R. P., van Venrooij, W. J. cDNA cloning of the human U1 snRNA-associated A protein: extensive homology between U1 and U2 snRNP-specific proteins. EMBO J. 6: 3841-3848, 1987.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

31 kDa

Gene Name Synonym

EGF like domain multiple 6

Subcellular Location

Basement membrane.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.