Anti-RIN1 Antibody Picoband®

About this product

Boster Bio Anti-RIN1 Antibody Picoband® catalog # A04953-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04953-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ras and Rab interactor 1 is a protein that in humans is encoded by the RIN1 gene. Predicted to enable small GTPase binding activity. Predicted to be involved in endocytosis; regulation of catalytic activity; and signal transduction. Predicted to act upstream of or within associative learning; memory; and negative regulation of synaptic plasticity. Located in cytoplasm and plasma membrane.

Synonyms

Prolactin regulatory element-binding protein; Mammalian guanine nucleotide exchange factor mSec12; PREB; SEC12

Gene Name

RIN1

Gene ID

9610

UniProt

Q13671

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RIN1 recombinant protein (Position: A76-N669) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. .

Applications

WB, Flow Cytometry, ELISA

Field of Research

Epigenetics and Nuclear Signaling, Transcription

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. .

References & Citations

1. Colicelli, J., Nicolette, C., Birchmeier, C., Rodgers, L., Riggs, M., Wigler, M. Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae. Proc. Nat. Acad. Sci. 88: 2913-2917, 1991. 2. Han, L., Colicelli, J. A human protein selected for interference with Ras function interacts ly with Ras and competes with Raf1. Molec. Cell. Biol. 15: 1318-1323, 1995. 3. Han, L., Wong, D., Dhaka, A., Afar, D., White, M., Xie, W., Herschman, H., Witte, O., Colicelli, J. Protein binding and signaling properties of RIN1 suggest a unique effector function. Proc. Nat. Acad. Sci. 94: 4954-4959, 1997.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

45468 MW

Observed Molecular Weight

90 kDa

Applications Notes

6

Gene Name Synonym

Prolactin regulatory element-binding protein

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass membrane protein . Nucleus . Concentrates at endoplasmic reticulum exit sites. .

Protein Name

Vesicular acetylcholine transporter

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.