Anti-PGAM1 Antibody Picoband®

About this product

Boster Bio Anti-PGAM1 Antibody Picoband® catalog # A04470-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04470-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a mutase that catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

Integrin alpha-L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD11a; ITGAL; CD11A

Gene Name

PGAM1

Gene ID

5223

UniProt

P18669

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PGAM1 recombinant protein (Position: Q43-K254) .

Clonality

Polyclonal

Tissue Specificity

Leukocytes.

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Field of Research

Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Signal Transduction, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.

References & Citations

1. Charles, D. J., Pretsch, W. Linear dose-response relationship of erythrocyte enzyme-activity mutations in offspring of ethylnitrosourea-treated mice. Mutat. Res. 176: 81-91, 1987. 2. Chen, S.-H., Anderson, J., Giblett, E. R., Lewis, M. Phosphoglyceric acid mutase: rare genetic variants and tissue distribution. Am. J. Hum. Genet. 26: 73-77, 1974. 3. Chen, S.-H., Anderson, J. E., Giblett, E. R. Human red cell 2,3-diphosphogl ycerate mutase and monophosphoglycerate mutase: genetic evidence for two separate loci. Am. J. Hum. Genet. 29: 405-407, 1977.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

128770 MW

Observed Molecular Weight

29 kDa

Applications Notes

6

Gene Name Synonym

Integrin alpha-L

Subcellular Location

Membrane; Single-pass type I membrane protein.

Protein Name

Integrin alpha-L

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.