Anti-RTL3 Antibody Picoband®

About this product

Boster Bio Anti-RTL3 Antibody Picoband® catalog # A31819. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A31819

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Retrotransposon Gag like 3 is a protein that in humans is encoded by the RTL3 gene. This gene is a member of a family of gag-related retrotransposon genes. These genes appear to have lost the ability to retrotranspose; however, their open reading frames have remained intact, which may indicate that these genes have acquired new functions in the cell.

Synonyms

Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29

Gene Name

RTL3

Gene ID

203430

UniProt

Q8N8U3

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RTL3 recombinant protein (Position: Q168-Q475) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB, Flow Cytometry, ELISA

Field of Research

Chemokines, Immunology, Innate Immunity

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.

References & Citations

1. Jürgen Brandt, Schrauth, S. , Veith, A. M. , Froschauer, A. , Haneke, T. , & Schultheis, C. , et al. (2005) . Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals. Gene, 345 (1), 101-111. 2. Brandt, J. , Veith, A. M. , & Volff, J. N. . (2005) . A family of neofunctionalized ty3/gypsy retrotransposon genes in mammalian genomes. Cytogenetic & Genome Research, 110 (1-4), 307-317. 3. Ota, T. , Suzuki, Y. , Nishikawa, T. , Otsuki, T. , & Sugano, S. . (2004) . Complete sequencing and characterization of 21,243 full-length human cdnas. Nature Genetics, 36 (1), 40-45.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

14377 MW

Observed Molecular Weight

50 kDa

Applications Notes

6

Gene Name Synonym

Retrotransposon Gag like 10

Subcellular Location

Cell membrane; Lipid-anchor, GPI-anchor.

Protein Name

Lymphocyte antigen 6A-2/6E-1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.