Anti-RAB43 Antibody Picoband®

About this product

Boster Bio Anti-RAB43 Antibody Picoband® catalog # A09315-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A09315-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Ras-related GTP-binding protein 43 (RAB43) is a member ofthe Rassuperfamily. RAB43 is mainly located in endoplasmic reticulum and Golgi, and plays a role as a key regulator of vesicle movement, signal transduction and tethering membrane eventsin membrane trafficking.

Synonyms

B-cell differentiation antigen CD72; Lyb-2; CD72; CD72

Gene Name

RAB43

Gene ID

339122

UniProt

Q86YS6

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human RAB43 recombinant protein (Position: Q14-E206) .

Clonality

Polyclonal

Tissue Specificity

Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Applications

WB, ICC, IF, Flow Cytometry, ELISA

Field of Research

Adaptive Immunity, B Cells, Hematopoietic Progenitors, Immunology, Lymphoid, Stem Cells

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Plays a role in B-cell proliferation and differentiation.

References & Citations

1. Jiang, Y. , Sun, Y. , Hu, J. , Yu, N. , & Xu, H. . (2019) . A germline mutation in rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome. BMC Cancer, 19 (1) . 2. ChunmanLi, ZheWei, YiFan, WeiHuang, YunchaoSu, & HonglinLi, et al. (2017) . The gtpase rab43 controls the anterograde er-golgi trafficking and sorting of gpcrs. Cell Reports. 3. Ming-Zhi, Han, Bin, Huang, An-Jing, & Chen, et al. (2017) . High expression of rab43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas. Oncology reports.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

23 kDa

Applications Notes

6

Gene Name Synonym

CD72 molecule

Subcellular Location

Membrane; Single-pass type II membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.