Anti-PIANP Antibody Picoband®

About this product

Boster Bio Anti-PIANP Antibody Picoband® catalog # A14063-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A14063-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a ligand for the paired immunoglobin-like type 2 receptor alpha, and so may be involved in immune regulation. Alternate splicing results in multiple transcript variants encoding different proteins.

Synonyms

RNA-binding protein 47; RNA-binding motif protein 47; RBM47

Gene Name

PIANP

Gene ID

196500

UniProt

Q8IYJ0

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human PIANP recombinant protein (Position: R56-L282) .

Clonality

Polyclonal

Tissue Specificity

Abundantly expressed in tonsil, lymph node, and trachea; strong expression in prostate; lower expression in thyroid, stomach, and colon. .

Applications

WB, Flow Cytometry, ELISA

Field of Research

Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Can bind to the surface of B-lymphoma cells, but not T- lymphoma cells, consistent with a function as a secreted mediator acting upon B-cells.

References & Citations

1. Evdokimov, K., Biswas, S., Adrian, M., Weber, J., Schledzewski, K., Winkler, M., Goerdt, S., Geraud, C. Proteolytic cleavage of LEDA-1/PIANP by furin-like proprotein convertases precedes its plasma membrane localization. Biochem. Biophys. Res. Commun. 434: 22-27, 2013. 2. Geraud, C., Schledzewski, K., Demory, A., Klein, D., Kaus, M., Peyre, F., Sticht, C., Evdokimov, K., Lu, S., Schmieder, A., Goerdt, S. Liver sinusoidal endothelium: a microenvironment-dependent differentiation program in rat including the novel junctional protein liver endothelial differentiation-associated protein-1. Hepatology 52: 313-326, 2010. 3. Gross, M. B. Personal Communication. Baltimore, Md. 10/28/2014.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

64099 MW

Observed Molecular Weight

45 kDa

Applications Notes

6

Gene Name Synonym

RNA-binding protein 47

Subcellular Location

Nucleus .

Protein Name

Follicular dendritic cell secreted peptide

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.