Anti-PRPF6 Antibody Picoband®

About this product

Boster Bio Anti-PRPF6 Antibody Picoband® catalog # A06724-2. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A06724-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Pre-mRNA-processing factor 6 is a protein that in humans is encoded by the PRPF6 gene. The protein encoded by this gene appears to be involved in pre-mRNA splicing, possibly acting as a bridging factor between U5 and U4/U6 snRNPs in formation of the spliceosome. The encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.

Synonyms

Neurocan core protein; Chondroitin sulfate proteoglycan 3; NCAN; CSPG3, NEUR

Gene Name

PRPF6

Gene ID

55015

UniProt

O94906

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PRPF6 recombinant protein (Position: K61-K585) .

Clonality

Polyclonal

Tissue Specificity

Brain.

Applications

WB, ICC, IF, Flow Cytometry, ELISA

Field of Research

Cell Adhesion Proteins, ECM Proteins, Neuroscience

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM) . Chondroitin sulfate proteoglycan; binds to hyaluronic acid.

References & Citations

1. Fan, S., Goto, K., Chen, G., Morinaga, H., Nomura, M., Okabe, T., Nawata, H., Yanase, T. Identification of the functional domains of ANT-1, a novel coactivator of the androgen receptor. Biochem. Biophys. Res. Commun. 341: 192-201, 2006. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 5/16/2011. 3. Makarov, E. M., Makarova, O. V., Achsel, T., Luhrmann, R. The human homologue of the yeast splicing factor Prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions. J. Molec. Biol. 298: 567-575, 2000.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

104553 MW

Observed Molecular Weight

107 kDa

Applications Notes

6

Gene Name Synonym

Neurocan

Subcellular Location

Secreted .

Protein Name

AP-2 complex subunit beta

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.