Anti-POH1/PSMD14 Antibody Picoband®

About this product

Boster Bio Anti-POH1/PSMD14 Antibody Picoband® catalog # A06584-1. Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A06584-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

26S proteasome non-ATPase regulatory subunit 14, also known as 26S proteasome non-ATPase subunit Rpn11, is an enzyme that in humans is encoded by the PSMD14 gene. This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.

Synonyms

Semaphorin-3B; Sema A (V) ; Semaphorin-V; Sema V; SEMA3B; SEMA5; SEMAA

Gene Name

PSMD14

Gene ID

10213

UniProt

O00487

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human POH1/PSMD14 recombinant protein (Position: D21-K310) .

Clonality

Polyclonal

Tissue Specificity

Expressed abundantly but differentially in a variety of neural and nonneural tissues.

Applications

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

Field of Research

Adapters, Coat Proteins, Cytoplasmic, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

References & Citations

1. Spataro, V., Toda, T., Craig, R., Seeger, M., Dubiel, W., Harris, A. L., Norbury, C. Resistance to diverse drugs and ultraviolet light conferred by overexpression of a novel human 26 S proteasome subunit. J. Biol. Chem. 272: 30470-30475, 1997. 2. Yao, T., Cohen, R. E. A cryptic protease couples deubiquitination and degradation by the proteasome. Nature 419: 403-407, 2002.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

104553 MW

Observed Molecular Weight

36 kDa

Applications Notes

6

Gene Name Synonym

Semaphorin 3B

Subcellular Location

Endoplasmic reticulum. Secreted.

Protein Name

AP-2 complex subunit beta

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.