Anti-PHF1 Antibody Picoband®

About this product

Boster Bio Anti-PHF1 Antibody Picoband® catalog # A03758-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03758-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene. This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27) -specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Sodium/glucose cotransporter 2; Na (+) /glucose cotransporter 2; Low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2; SLC5A2; SGLT2

Gene Name

PHF1

Gene ID

5252

UniProt

O43189

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human PHF1 recombinant protein (Position: L31-H491) .

Clonality

Polyclonal

Applications

WB, ELISA

Field of Research

Cancer, Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Sodium-dependent glucose transporter. Has a Na+ to glucose coupling ratio of 1:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na+/glucose cotransporter arranged in series along kidney proximal tubules.

References & Citations

1. Coulson, M., Robert, S., Eyre, H. J., Saint, R. The identification and localization of a human gene with sequence similarity to Polycomblike of Drosophila melanogaster. Genomics 48: 381-383, 1998.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

62 kDa

Gene Name Synonym

Solute carrier family 5 member 2

Subcellular Location

Membrane. Multi-pass membrane protein.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.