Anti-RUFY1 Antibody Picoband®

About this product

Boster Bio Anti-RUFY1 Antibody Picoband® catalog # A10201-1. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A10201-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

RUN and FYVE domain-containing protein 1 is a protein that in humans is encoded by the RUFY1 gene. This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

Protein NDRG3; N-myc downstream-regulated gene 3 protein; NDRG3

Gene Name

RUFY1

Gene ID

80230

UniProt

Q96T51

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human RUFY1 recombinant protein (Position: L20-Q650) .

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Highly expressed in brain. .

Applications

WB, Flow Cytometry, ELISA

Field of Research

Cancer, Cell Biology, Cell Cycle, Cell Differentiation, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.

References & Citations

1. Yang, J., Kim, O., Wu, J., Qiu, Y. Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1: a possible role of ETK in regulation of vesicle trafficking. J. Biol. Chem. 277: 30219-30226, 2002.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

41409 MW

Observed Molecular Weight

80 kDa

Applications Notes

6

Gene Name Synonym

Protein NDRG3

Subcellular Location

Membrane ; Single-pass type I membrane protein .

Protein Name

Protein NDRG3

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.