Anti-NT5C Antibody Picoband®

About this product

Boster Bio Anti-NT5C Antibody Picoband® catalog # A10650-1. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A10650-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

5', 3'-nucleotidase, cytosolic, also known as 5' (3') -deoxyribonucleotidase, cytosolic type (cdN) or deoxy-5'-nucleotidase 1 (dNT-1), is an enzyme that in humans is encoded by the NT5C gene on chromosome 17. This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2' (3') -dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.

Synonyms

RNA-binding protein Nova-2; Astrocytic NOVA1-like RNA-binding protein; Neuro-oncological ventral antigen 2; NOVA2; ANOVA; NOVA3

Gene Name

NT5C

Gene ID

30833

UniProt

Q8TCD5

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human NT5C recombinant protein (Position: H35-R179) .

Clonality

Polyclonal

Tissue Specificity

Brain. Expression restricted to astrocytes.

Applications

WB, IHC, Flow Cytometry, ELISA

Field of Research

Channels, Metabolism, Plasma Membrane, Signal Transduction

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

May regulate RNA splicing or metabolism in a specific subset of developing neurons. Binds single strand RNA.

References & Citations

1. Anderson, J. A., Teng, Y.-S., Giblett, E. R. Stains for six enzymes potentially applicable to chromosomal assignment by cell hybridization. Cytogenet. Cell Genet. 14: 295-299, 1975. 2. Hoglund, L., Reichard, P. Cytoplasmic 5-prime (3-prime) -nucleotidase from human placenta. J. Biol. Chem. 265: 6589-6595, 1990. 3. Paglia, D. E., Valentine, W. N., Brockway, R. A. Identification of thymidine nucleotidase and deoxyribonucleotidase activities among normal isozymes of 5-prime-nucleotidase in human erythrocytes. Proc. Nat. Acad. Sci. 81: 588-592, 1984.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

29370 MW

Observed Molecular Weight

24 kDa

Applications Notes

6

Gene Name Synonym

NOVA alternative splicing regulator 2

Subcellular Location

Nucleus.

Protein Name

Aquaporin-6

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.