Anti-Alpha 1 microglobulin/Ambp Antibody Picoband®

About this product

Boster Bio Anti-Alpha 1 microglobulin/Ambp Antibody Picoband® catalog # A02419-4. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02419-4

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Protein AMBP is a protein that in humans is encoded by the AMBP gene. This gene encodes a fusion protein that undergoes proteolytic processing to generate two mature proteins: alpha-1-microglobulin (A1m) is a heme-binding plasma glycoprotein of the lipocalin superfamily of proteins that bind to hydrophobic molecules, whereas bikunin belongs to the superfamily of Kunitz-type protease inhibitors. The transgenic mice specifically lacking bikunin, but not A1m, exhibit female infertility and an increased sensitivity to lung metastasis.

Synonyms

Protein AMBP; Alpha-1-microglobulin; Protein HC; Alpha-1 microglycoprotein; Complex-forming glycoprotein heterogeneous in charge; Inter-alpha-trypsin inhibitor light chain; ITI-LC; Bikunin; EDC1; HI-30; Uronic-acid-rich protein; Trypstatin; AMBP; HCP; ITIL

Gene Name

Ambp

Gene ID

11699

UniProt

Q07456

Host

Rabbit

Reactivity

Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse Alpha 1 microglobulin/Ambp recombinant protein (Position: A205-S349) .

Clonality

Polyclonal

Tissue Specificity

Expressed by the liver and secreted in plasma. Alpha-1-microglobulin occurs in many physiological fluids including plasma, urine, and cerebrospinal fluid. Inter-alpha- trypsin inhibitor is present in plasma and urine.

Applications

WB, ELISA

Field of Research

Cancer, Cardiovascular, Cell Biology, Protease Inhibitors, Proteolysis/Ubiquitin, Serum Proteins, Tumor Biomarkers

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

References & Citations

1. Diarra-Mehrpour, M., Bourguignon, J., Sesboue, R., Mattei, M.-G., Passage, E., Salier, J.-P., Martin, J.-P. Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes. Europ. J. Biochem. 179: 147-154, 1989. 2. Hochstrasser, K., Bretzel, G., Feuth, H., Hilla, W., Lempart, K. The inter-alpha-trypsin inhibitor as precursor of the acid-stable proteinase inhibitors in human serum and urine. Hoppe Seylers Z. Physiol. Chem. 357: 153-162, 1976. 3. Leveillard, T., Bourguignon, J., Sesboue, R., Hanauer, A., Salier, J. P., Diarra-Mehrpour, M., Martin, J. P. BstXI RFLP in the human inter-alpha-trypsin inhibitor light chain gene. Nucleic Acids Res. 16: 2744 only, 1988.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

39 kDa

Gene Name Synonym

Alpha-1-microglobulin

Subcellular Location

Secreted.

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.