Anti-MINDY4 Antibody Picoband®

About this product

Boster Bio Anti-MINDY4 Antibody Picoband® catalog # A32449-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A32449-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

MINDY lysine 48 deubiquitinase 4, also known as MINDY4, is a human gene. MINDY4 (MINDY Lysine 48 Deubiquitinase 4, also designated AQP1, AQP-1, CHIP28, C7orf67, and FAM188B) is a protein coding gene located on human chromosome 7p14.3. The human MINDY4 gene encodes a 757 amino acids protein containing 84372 Da. The MINDY4 protein is broadly expressed in testis, lung and other tissues. The MINDY4 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, and frog. 330 organisms have orthologs with human gene MINDY4. MINDY4B is an important paralog of this MINDY4 gene.

Synonyms

70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70 (S6K) alpha antibody, p70 (S6K) -alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Gene Name

MINDY4

Gene ID

84182

UniProt

Q4G0A6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross reactivity with other proteins.

Immunogen

E.coli-derived human MINDY4 recombinant protein (Position: E414-Q685) . Human MINDY4 shares 87.5% amino acid (aa) sequence identity with mouse MINDY4.

Clonality

Polyclonal

Tissue Specificity

Expressed in all tissues.

Applications

WB, IHC, ELISA

Field of Research

Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway.

References & Citations

1. Urabe, Y., Tanikawa, C., Takahashi, A., Okada, Y., Morizono, T., Tsunoda, T., ... & Matsuda, K. (2012) . A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible Loci at 5q35. 3, 7p14. 3, and 13q14. 1. PLoS genetics, 8 (3), e1002541. 2. Choi, E. S., Lee, H., Sung, J. Y., Lee, C. H., Jang, H., Kim, K. T., ... & Goh, S. H. (2018) . FAM188B enhances cell survival via interaction with USP7. Cell death & disease, 9 (6), 633. 3. Kwasna, D., Rehman, S. A. A., Natarajan, J., Matthews, S., Madden, R., De Cesare, V., ... & Kulathu, Y. (2018) . Discovery and characterization of ZUFSP/ZUP1, a distinct deubiquitinase class important for genome stability. Molecular cell, 70 (1), 150-164.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

52588 MW

Observed Molecular Weight

72 kDa

Gene Name Synonym

Serine/threonine-protein kinase AtPK1/AtPK6

Subcellular Location

Cytoplasm. Nucleus.

Protein Name

Serine/threonine-protein kinase AtPK1/AtPK6

Isotype

IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.