Anti-ARHGEF7 Antibody Picoband®

About this product

Boster Bio Anti-ARHGEF7 Antibody Picoband® catalog # A02764-2. Tested in WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A02764-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Rho guanine nucleotide exchange factor 7 is a protein that in humans is encoded by the ARHGEF7 gene. This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Gene Name

ARHGEF7

Gene ID

8874

UniProt

Q14155

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human ARHGEF7 recombinant protein (Position: S25-N637) . Human ARHGEF7 shares 90.4% amino acid (aa) sequence identity with mouse ARHGEF7.

Clonality

Polyclonal

Applications

WB, IHC, ICC, IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L., Cerione, R. A. A novel regulator of p21-activated kinases. J. Biol. Chem. 273: 23633-23636, 1998. 2. Feng, Q., Baird, D., Peng, X., Wang, J., Ly, T., Guan, J.-L., Cerione, R. A. Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. Nature Cell Biol. 8: 945-956, 2006. 3. Manser, E., Loo, T.-H., Koh, C.-G., Zhao, Z.-S., Chen, X.-Q., Tan, L., Tan, I., Leung, T., Lim, L. PAK kinases are ly coupled to the PIX family of nucleotide exchange factors. Molec. Cell 1: 183-192, 1998.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

80 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.