Anti-MSL3 Antibody Picoband®

About this product

Boster Bio Anti-MSL3 Antibody Picoband® catalog # A04993-1. Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A04993-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Y+L amino acid transporter 1 is a protein that in humans is encoded by the SLC7A7 gene. The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI) . Alternative splicing results in multiple transcript variants.

Gene Name

MSL3

Gene ID

10943

UniProt

Q8N5Y2

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human SLC7A7 recombinant protein (Position: M1-D498) . Human SLC7A7 shares 90.8% and 91.6% amino acid (aa) sequence identity with mouse and rat SLC7A7, respectively.

Clonality

Polyclonal

Applications

ELISA, WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Basilicata, M. F., Bruel, A.-L., Semplicio, G., Valsecchi, C. I. K., Aktas, T., Duffourd, Y., Rumpf, T., Morton, J., Bache, I., Szymanski, W. G., Gilissen, C., Vanakker, O., and 29 others. De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nature Genet. 50: 1442-1451, 2018. 2. Brunet, T., McWalter, K., Mayerhanser, K., Anbouba, G. M., Armstrong-Javors, A., Bader, I., Baugh, E., Begtrup, A., Bupp, C. P., Callewaert, B. L., Cereda, A., Cousin, M. A., and 49 others. Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder. Genet. Med. 23: 384-395, 2021. 3. Prakash, S. K., Van den Veyver, I. B., Franco, B., Volta, M., Ballabio, A., Zoghbi, H. Y. Characterization of a novel chromo domain gene in Xp22.3 with homology to Drosophila msl-3. Genomics 59: 77-84, 1999.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

70 kDa

Isotype

IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.