Anti-IRF2BP1 Antibody Picoband®

About this product

Boster Bio Anti-IRF2BP1 Antibody Picoband® catalog # A11406-2. Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A11406-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

IRF2BP1 (Interferon regulatory factor 2 binding protein 1) is a 64-66 kDa member of the IFR2BP family of proteins. It is widely expressed, and known to bind to the C-terminus of IRF-2, creating a transcriptional repressor complex. IRF2BP1 also bind to JDP2 (Jun dimerization protein 2), promoting its ubiquitination. Human IRF2BP1 is 584 amino acids (aa) in length. It contains two Zn-finger domains (aa 6-67 and 498-584), one coiled-coil region (aa 197-217), a Cys-rich region (aa 503?550), an N-terminal acetylation site at Ala2, and multiple utilized phosphorylation sites at Ser 66/125/186/384/421/436/453/457. Over aa 188-356, human and mouse IRF2BP1 are identical in amino acid sequence.

Gene Name

IRF2BP1

Gene ID

26145

UniProt

Q8IU81

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human IRF2BP1 recombinant protein (Position: A71-D439) . Human IRF2BP1 shares 95.1% amino acid (aa) sequence identity with mouse IRF2BP1.

Clonality

Polyclonal

Applications

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Childs, K. S., Goodbourn, S. Identification of novel co-repressor molecules for interferon regulatory factor-2. Nucleic Acids Res. 31: 3016-3026, 2003. 2. Gross, M. B. Personal Communication. Baltimore, Md. 7/23/2013. 3. Kimura, M. IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription. FEBS Lett. 582: 2833-2837, 2008.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Observed Molecular Weight

72 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.