Anti-PLCB2 Antibody Picoband®

About this product

Boster Bio Anti-PLCB2 Antibody Picoband® catalog # A05927-2. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05927-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2 is an enzyme that in humans is encoded by the PLCB2 gene. The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses.

Gene Name

PLCB2

Gene ID

5330

UniProt

Q00722

Host

Rabbit

Reactivity

Human

Immunogen

E.coli-derived human PLCB2 recombinant protein (Position: D27-L1185) . Human PLCB2 shares 85.7% and 85.3% amino acid (aa) sequence identity with mouse and rat PLCB2, respectively.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Lee, S. B., Rao, A. K., Lee, K.-H., Yang, X., Bae, Y. S., Rhee, S. G. Decreased expression of phospholipase C-b2 isozyme in human platelets with impaired function. Blood 88: 1684-1691, 1996. 2. Li, Z., Jiang, H., Xie, W., Zhang, Z., Smrcka, A. V., Wu, D. Roles of PLC-beta-2 and -beta-3 and PI3K-gamma in chemoattractant-mediated signal transduction. Science 287: 1046-1049, 2000. 3. Mao, G. F., Vaidyula, V. R., Kunapuli, S. P., Rao, A. K. Lineage-specific defect in gene expression in human platelet phospholipase C-beta-2 deficiency. Blood 99: 905-911, 2002.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

134 kDa

Observed Molecular Weight

140 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.