Anti-GANAB Antibody Picoband®

About this product

Boster Bio Anti-GANAB Antibody Picoband® catalog # A09668-2. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A09668-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Neutral alpha-glucosidase AB is an enzyme that in humans is encoded by the GANAB gene. This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

Gene Name

GANAB

Gene ID

23193

UniProt

Q14697

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

E.coli-derived human GANAB recombinant protein (Position: Q68-R944) . Human GANAB shares 92% amino acid (aa) sequence identity with mouse GANAB.

Clonality

Polyclonal

Applications

ELISA, Flow Cytometry, IF, IHC, ICC, WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Besse, W., Choi, J., Ahram, D., Mane, S., Sanna-Cherchi, S., Torres, V., Somlo, S. A noncoding variant in GANAB explains isolated polycystic liver disease (PCLD) in a large family. Hum. Mutat. 39: 378-382, 2018. 2. Martiniuk, F., Smith, M., Desnick, R., Astrin, K., Mitra, J., Hirschhorn, R. Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11. (Abstract) Am. J. Hum. Genet. 34: 173A only, 1982. 3. Martiniuk, F., Smith, M., Ellenbogen, A., Desnick, R. J., Astrin, K., Mitra, J., Hirschhorn, R. Assignment of the gene for neutral alpha-glucosidase AB to chromosome 11. Cytogenet. Cell Genet. 35: 110-116, 1983.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

107 kDa

Observed Molecular Weight

100 kDa

Applications Notes

6

Isotype

IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.