Anti-TXNDC3/NME8 Antibody Picoband®

About this product

Boster Bio Anti-TXNDC3-NME8 Antibody Picoband® catalog # A08723-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08723-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.

Synonyms

NME8; SPTRX2; TXNDC3; Thioredoxin domain-containing protein 3; NM23-H8; NME/NM23 family member 8; Spermatid-specific thioredoxin-2; Sptrx-2

Gene Name

NME8

Gene ID

51314

UniProt

Q8N427

Host

Rabbit

Reactivity

Human, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human TXNDC3/NME8 recombinant protein (Position: M1-H446) . Human TXNDC3/NME8 shares 63% and 61.2% amino acid (aa) sequence identity with mouse and rat TXNDC3/NME8, respectively.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Duriez, B., Duquesnoy, P., Escudier, E., Bridoux, A.-M., Escalier, D., Rayet, I., Marcos, E., Vojtek, A.-M., Bercher, J.-F., Amselem, S. A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia. Proc. Nat. Acad. Sci. 104: 3336-3341, 2007. Note: Erratum: Proc. Nat. Acad. Sci. 104: 6490 only, 2007. 2. Sadek, C. M., Damdimopoulos, A. E., Pelto-Huikko, M., Gustafsson, J.-A., Spyrou, G., Miranda-Vizuete, A. Sptrx-2, a fusion protein composed of one thioredoxin and three tandemly repeated NDP-kinase domains is expressed in human testis germ cells. Genes Cells 6: 1077-1090, 2001.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

67 kDa

Observed Molecular Weight

67 kDa

Applications Notes

6

Gene Name Synonym

NME/NM23 family member 8

Protein Name

Thioredoxin domain-containing protein 3

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.