Anti-DEPDC6/DEPTOR Antibody Picoband®

About this product

Boster Bio Anti-DEPDC6-DEPTOR Antibody Picoband® catalog # A03811-2. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A03811-2

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

DEP domain-containing mTOR-interacting protein (DEPTOR) also known as DEP domain-containing protein 6 (DEPDC6) is a protein that in humans is encoded by the DEPTOR gene. Enables phosphatidic acid binding activity and protein serine/threonine kinase inhibitor activity. Involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. Is active in lysosomal membrane.

Synonyms

DEPTOR; DEPDC6; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6

Gene Name

DEPTOR

Gene ID

64798

UniProt

Q8TB45

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human DEPDC6/DEPTOR recombinant protein (Position: A22-C409) . Human DEPDC6/DEPTOR shares 97.9% amino acid (aa) sequence identity with mouse DEPDC6/DEPTOR.

Clonality

Polyclonal

Applications

WB, IHC, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Hartz, P. A. Personal Communication. Baltimore, Md. 8/20/2009. 2. Peterson, T. R., Laplante, M., Thoreen, C. C., Sancak, Y., Kang, S. A., Kuehl, W. M., Gray, N. S., Sabatini, D. M. DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell 137: 873-886, 2009.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

46 kDa

Observed Molecular Weight

48 kDa

Applications Notes

6

Gene Name Synonym

DEP domain containing MTOR interacting protein

Protein Name

DEP domain-containing mTOR-interacting protein

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.