Anti-CTNNBL1 Antibody Picoband®

About this product

Boster Bio Anti-CTNNBL1 Antibody Picoband® catalog # A05286-1. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05286-1

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

Beta-catenin-like protein 1 is a protein that in humans is encoded by the CTNNBL1 gene. The protein encoded by this gene is a component of the pre-mRNA-processing factor 19-cell division cycle 5-like (PRP19-CDC5L) protein complex, which activates pre-mRNA splicing and is an integral part of the spliceosome. The encoded protein is also a nuclear localization sequence binding protein, and binds to activation-induced deaminase and is important for antibody diversification. This gene may also be associated with the development of obesity. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome.

Synonyms

CTNNBL1; C20orf33; PP8304; Beta-catenin-like protein 1; Nuclear-associated protein; NAP; Testis development protein NYD-SP19

Gene Name

CTNNBL1

Gene ID

56259

UniProt

Q8WYA6

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human CTNNBL1 recombinant protein (Position: Q122-E231) . Human CTNNBL1 shares 97.3% and 98.2% amino acid (aa) sequence identity with mouse and rat CTNNBL1, respectively.

Clonality

Polyclonal

Applications

WB, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Conticello, S. G., Ganesh, K., Xue, K., Lu, M., Rada, C., Neuberger, M. S. Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1. Molec. Cell 31: 474-484, 2008. 2. Ganesh, K., Adam, S., Taylor, B., Simpson, P., Rada, C., Neuberger, M. CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31. J. Biol. Chem. 286: 17091-17102, 2011. 3. Jabbour, L., Welter, J. F., Kollar, J., Hering, T. M. Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis. Genomics 81: 292-303, 2003.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

65 kDa

Observed Molecular Weight

65 kDa

Applications Notes

6

Gene Name Synonym

Catenin beta like 1

Protein Name

Beta-catenin-like protein 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.