Anti-MINPP1 Antibody Picoband®

About this product

Boster Bio Anti-MINPP1 Antibody Picoband® catalog # A08462-3. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08462-3-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

His gene encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.

Synonyms

MINPP1; MIPP; UNQ900/PRO1917; Multiple inositol polyphosphate phosphatase 1; EC 3.1.3.62; 2,3-bisphosphoglycerate 3-phosphatase; 2,3-BPG phosphatase; EC 3.1.3.80; Inositol; 1,3,4,5-tetrakisphosphate 3-phosphatase; Ins (1,3,4,5P (4 3-phosphatase

Gene Name

MINPP1

Gene ID

9562

UniProt

Q9UNW1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human MINPP1 recombinant protein (Position: R155-H421) . Human MINPP1 shares 89.5% and 89.9% amino acid (aa) sequence identity with mouse and rat MINPP1, respectively.

Clonality

Polyclonal

Applications

WB, IHC, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Appelhof, B., Wagner, M., Hoefele, J., Heinze, A., Roser, T., Koch-Hogrebe, M., Roosendaal, S. D., Dehghani, M., Mehrjardi, M. Y. V., Torti, E., Houlden, H., Maroofian, R., Rajabi, F., Sticht, H., Baas, F., Wieczorek, D., Jamra, R. A. Pontocerebellar hypoplasia due to bi-allelic variants in MINPP1. Europ. J. Hum. Genet. 29: 411-421, 2021. 2. Caffrey, J. J., Hidaka, K., Matsuda, M., Hirata, M., Shears, S. B. The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification. FEBS Lett. 442: 99-104, 1999. 3. Chi, H., Tiller, G. E., Dasouki, M. J., Romano, P. R., Wang, J., O'Keefe, R. J., Puzas, J. E., Rosier, R. N., Reynolds, P. R. Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. Genomics 56: 324-336, 1999.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

55 kDa

Observed Molecular Weight

47 kDa

Applications Notes

6

Gene Name Synonym

Multiple inositol-polyphosphate phosphatase 1

Protein Name

Multiple inositol polyphosphate phosphatase 1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.