Anti-MPP5/PALS1 Antibody Picoband®

About this product

Boster Bio Anti-MPP5/PALS1 Antibody Picoband® catalog # A05311-2. Tested in WB, IHC, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A05311-2-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289) . Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms

Protein PALS1; Protein associated with Lin-7 1; PALS1; Membrane protein; palmitoylated 5; MAGUK p55 subfamily member 5

Gene Name

PALS1

Gene ID

64398

UniProt

Q8N3R9

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human MPP5/PALS1 recombinant protein (Position: R86-D386) . Human MPP5/PALS1 shares 95.7% and 96.7% amino acid (aa) sequence identity with mouse and rat MPP5/PALS1, respectively.

Clonality

Polyclonal

Applications

WB, IHC, IP, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Kamberov, E., Makarova, O., Roh, M., Liu, A., Karnak, D., Straight, S., Margolis, B. Molecular cloning and characterization of Pals, proteins associated with mLin-7. J. Biol. Chem. 275: 11425-11431, 2000. 2. Roh, M. H., Makarova, O., Liu, C.-J., Shin, K., Lee, S., Laurinec, S., Goyal, M., Wiggins, R., Margolis, B. The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost. J. Cell Biol. 157: 161-172, 2002. 3. Tseng, T.-C., Marfatia, S. M., Bryant, P. J., Pack, S., Zhuang, A., O'Brien, J. E., Lin, L., Hanada, T., Chishti, A. H. VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain. Biochim. Biophys. Acta 1518: 249-259, 2001.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

77kDa

Observed Molecular Weight

80 kDa

Applications Notes

6

Gene Name Synonym

Protein associated with LIN7 1, MAGUK p55 family member

Protein Name

Protein PALS1

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.