Anti-POLD4 Antibody Picoband®

About this product

Boster Bio Anti-POLD4 Antibody Picoband® catalog # A08778-1. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Specifications

Catalog number

A08778-1-carrier-free

Size / count

100 µg/Vial

Dry ice

No

Hazardous

No

Discontinued

No

Background

This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms

POLD4; POLDS; DNA polymerase delta subunit 4; DNA polymerase delta subunit p12

Gene Name

POLD4

Gene ID

57804

UniProt

Q9HCU8

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

E.coli-derived human POLD4 recombinant protein (Position: M1-L107) . Human POLD4 shares 83.2% amino acid (aa) sequence identity with mouse POLD4.

Clonality

Polyclonal

Applications

WB, ICC/IF, Flow Cytometry, ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

References & Citations

1. Gross, M. B. Personal Communication. Baltimore, Md. 4/9/2018. 2. Liu, G., Warbrick, E. The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins. Biochem. Biophys. Res. Commun. 349: 360-366, 2006. 3. Liu, L., Mo, J., Rodriguez-Belmonte, E. M., Lee, M. Y. W. T. Identification of a fourth subunit of mammalian DNA polymerase delta. J. Biol. Chem. 275: 18739-18744, 2000.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

12 kDa

Observed Molecular Weight

12 kDa

Applications Notes

6

Gene Name Synonym

DNA polymerase delta 4, accessory subunit

Protein Name

DNA polymerase delta subunit 4

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.